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dc.contributor.authorChapple, Claire Louise-
dc.descriptionPhd Thesisen_US
dc.description.abstractThe importance of monitoring, and where possible reducing, the level of radiation dose from diagnostic X-ray examinations has been recognised for many years and is becoming of increasing concern. Dose reduction is of particular concern in paediatric radiology, and there are specific problems associated with the monitoring and comparison of radiation doses to children. Any optimisation study relies on a framework of good dosimetry. Two techniques have been developed to improve the collection of patient dose data: the automation of survey techniques to increase the quantity of data collected; and a method of correcting for patient size which reduces one source of variability in the data. An optimisation strategy has been developed, consisting of theoretical simulations, experimental verification and clinical implementation. Monte Carlo techniques were used for the theoretical study, which investigated the effect of beam filtration on radiation dose and image quality for a wide range of parameters, specifically for a neonatal size phantom. Simulations included both radiography of bone in soft tissue and fluoroscopy of iodine and barium based contrast media. The results were assessed in terms of the beam spectra and the absorption and transmission characteristics of the phantom and image receptor. Experimental measurements of dose and contrast were made for a simple slab phantom corresponding to that simulated, and results showed good agreement with those predicted. A further set of experimental measurements were carried out using anthropomorphic phantoms in a clinical setting, which demonstrated how the theoretical predictions translated to clinical practice. A clinical trial of the use of a 0.1mm copper filter for fluoroscopic examinations of infants was performed, and the filter shown to give substantial dose reduction with no significant loss in image quality. Some general recommendations on dose quantities and the application of optimisation strategies to paediatric radiology have been made.en_US
dc.description.sponsorshipDistrict Research Committee of Newcastle Health Authority. National Health Service Locally Organised Research Committee of the Northern Regional Health Authority.en_US
dc.publisherNewcastle Universityen_US
dc.titleThe optimisation of radiation dose in paediatric radiologyen_US
Appears in Collections:Institute of Human Genetics

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